Brief Outline of Job: To develop a robust, transferable and flexible real-time release testing (RTRT) framework through the utilisation of a smart assembly of soft and hard sensors paired with big data approaches. This ambitious aim will be realised by working closely with the entire project team in the UK and US. You will have a PhD in a relevant subject (Electrical Engineering, Computer Science, Chemical Engineering, Pharmaceutical Science, Chemistry or related discipline) with appropriate experience in process and data analytics or related. You will develop novel data-driven methods for quality control applications of the next generation of medicines. Model…
Brief Outline of Job: To develop models and optimisation & machine learning methods to autonomously manufacture and test microscale tablet and capsule batches that contribute. This will include the development of process and formulation optimisers as well as self-optimised process and product models. The ambitious Autonomous MicroScale Manufacturing Platform will be realised by working closely with the entire project team and industrial partners, understanding challenges, proposing solutions as well as developing and implementing industrial digital technologies. You will have a PhD in a relevant subject (Chemical Engineering, Pharmaceutical Sciences, Mechanical Engineering, Chemistry, Physics, Computer Science or related discipline) with appropriate…
Description of the project: In the framework of a project financed by the Haut de France region (START'AIIR Program), we are recruiting a lab technician (in French “ingénieur d’étude”, IgE) at the University of Lille. He/she will be attached to the project leaders of the 2 laboratories UMET (Faculty of Sciences and Technologies) and INSERM U1008 (UFR3s) of the University of Lille. The IgE will work with a PhD student and/or a Master 2 student on the project to develop a bone glue for maxillofacial and orthopedic surgery. The IgE recruited will be in charge of optimizing the development process,…
University of Helsinki has an opening for a 18-month PostDoc position in ultrasensitive analytical technologies of advanced pharmaceutical systems. This position is part of a project that aims for successful development of dosage forms based on solid dispersions combining new/state-of-the-art solid dispersion production and ultra-sensitive analytical technologies. The appointee will perform research on the novel analytical characterization of the solid dispersions and biorelevant performance testing. We are looking for a person with a PhD degree in chemistry or other relevant background with expertise in analytics, especially in spectroscopic methods (FTIR, Raman, UV/Vis) and in XRPD and DSC. More information can…
Thursday, 19 September 2019 08:45

13th PSSRC Annual Meeting at the HHU

The annual meeting in Duesseldorf
Thursday, 08 November 2018 13:03

12th PSSRC Meeting in Leuven in Belgium

The twelfth annual meeting of the Pharmaceutical Solid State Research Cluster was held in Leuven (University of Leuven, KU Leuven) from 12 to 14 September 2018. It was attended by 122 participants (91 during the closed days and 31 during the open day) from the member research groups and alumni across Europe.
A new method for measuring of molecular mobility in glassy materials has been developed using terahertz spectroscopy. The absorption level of amorphous drugs at terahertz frequencies below Tg correlates with the stability of the drug as an amorphous solid. The molecular mobility responsible for the glass crystallisation significantly decreases at around a universal value of 0.67 Tg. This explains why the commonly used rules of thumb for glasses to remain stable below 0.8 Tg or Tg – 20 K do not work reliably. These results reveal a unique and completely novel opportunity to predict and test the stability of amorphous…